US 12,251,208 B2
Time controlled medication
Uri Kartoun, Cambridge, MA (US); Zachary A. Silverstein, Austin, TX (US); and Sarbajit K. Rakshit, Kolkata (IN)
Assigned to INTERNATIONAL BUSINESS MACHINES CORPORATION, Armonk, NY (US)
Filed by INTERNATIONAL BUSINESS MACHINES CORPORATION, Armonk, NY (US)
Filed on Nov. 30, 2020, as Appl. No. 17/106,302.
Prior Publication US 2022/0168551 A1, Jun. 2, 2022
Int. Cl. A61B 5/07 (2006.01); A61K 9/20 (2006.01); A61M 31/00 (2006.01); B01J 13/04 (2006.01); B01J 13/22 (2006.01); G16H 20/10 (2018.01); A61J 3/00 (2006.01)
CPC A61B 5/07 (2013.01) [A61K 9/2086 (2013.01); A61M 31/002 (2013.01); B01J 13/04 (2013.01); B01J 13/22 (2013.01); G16H 20/10 (2018.01); A61B 2562/162 (2013.01); A61J 3/007 (2013.01); A61M 2205/18 (2013.01); A61M 2205/3553 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A computer-implemented method for providing medications to a patient with a time gap, the method comprising:
determining a dissolving pattern for the patient, the dissolving pattern including a medication dissolving rate for a first medication and a second medication prescribed to the patient and a filler dissolving rate for a filler selected so that the time gap is elapsed prior to the second medication being taken after the first medication, the medication dissolving rate and the filler dissolving rate being specific to the patient;
determining dimensions of the first medication and the second medication to correspond to a dosage of the prescribed first medication and the prescribed second medication, respectively, and dimensions of the filler to accomplish the time gap; and
based on determining a combination of the dimensions of the first medication, the second medication, and the filler contained in a multi-medication pill exceed a maximum pill size threshold for the patient, 3D printing a signal pill including at least the first medication, the filler, and an edible electronic circuit (EEC), the filler surrounding the EEC and the first medication surrounding the filler such that the first medication is dissolved prior to the filler being dissolved, the first medication and the filler 3D printed in accordance with the determined dimensions.