US 12,251,190 B2
NIRAF calibration sheath phantom
Emily Chernich, Somerville, MA (US); and Christopher Brushett, Cambridge, MA (US)
Assigned to Canon U.S.A., Inc., Melville, NY (US)
Filed by Canon U.S.A., Inc., Melville, NY (US)
Filed on Oct. 13, 2022, as Appl. No. 18/046,452.
Prior Publication US 2024/0122481 A1, Apr. 18, 2024
Int. Cl. A61B 5/00 (2006.01)
CPC A61B 5/0066 (2013.01) [A61B 5/0084 (2013.01)] 18 Claims
OG exemplary drawing
 
1. An apparatus, comprising:
an optical probe having a first light to illuminate a sample;
a detector for detecting a fluorescence of reflection of the first light for illuminating the sample;
a sheath configured to allow the optical probe to travel longitudinally through the sheath to perform a pullback,
wherein the sheath has a fluorescent coating of known emitted fluorescence or known range of emitted fluorescence on at least a portion of the sheath surface for detection by the detector, and
a processor configured to
receive an emitted fluorescence measurement value from the fluorescent coating
determine a slope of a linear response for the emitted fluorescence measurement value, and
use the slope of a linear response to calibrate a fluorescence linear response.