US 12,251,160 B2
Systems and methods for automated widefield optical coherence tomography angiography
David Huang, Portland, OR (US); Gangjun Liu, Portland, OR (US); and Yali Jia, Portland, OR (US)
Assigned to Oregon Health & Science University, Portland, OR (US)
Filed by Oregon Health & Science University, Portland, OR (US)
Filed on Sep. 6, 2022, as Appl. No. 17/903,881.
Application 17/903,881 is a continuation of application No. 16/308,901, granted, now 11,452,442, previously published as PCT/US2017/037622, filed on Jun. 15, 2017.
Claims priority of provisional application 62/350,526, filed on Jun. 15, 2016.
Prior Publication US 2023/0069484 A1, Mar. 2, 2023
Int. Cl. A61B 3/10 (2006.01); A61B 3/00 (2006.01); A61B 3/12 (2006.01); A61B 5/00 (2006.01); A61B 5/02 (2006.01); A61B 5/11 (2006.01)
CPC A61B 3/102 (2013.01) [A61B 3/0091 (2013.01); A61B 3/10 (2013.01); A61B 3/1241 (2013.01); A61B 5/0066 (2013.01); A61B 5/02007 (2013.01); A61B 5/1128 (2013.01); A61B 5/6814 (2013.01); A61B 5/7207 (2013.01); A61B 5/721 (2013.01); A61B 5/7214 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A computer-based method of adaptively scanning a sample in optical coherence tomography (OCT) imaging to eliminate motion artifact during acquisition, the method comprising:
acquiring, via an OCT scanner, an OCT B-scan at a fast-scan location;
acquiring, via the OCT scanner, an OCT angiography (OCTA) B-scan at the fast-scan location, wherein the OCTA B-scan indicates variation in repeated OCT B-scans at the fast-scan location;
calculating, while the OCT scanner is at the fast-scan location, an indicator of at least one of eye blinking from the OCT B-scan or eye motion from the OCTA B-scan;
maintaining the OCT scanner at the fast-scan location based on the calculated indicator, wherein the maintaining includes interrupting a progress of a slow-scan axis galvanometer mirror and maintaining the slow-scan axis galvanometer mirror at its current position; and
re-scanning the sample at the fast-scan location via the OCT scanner until the calculated indicator indicates that the at least one of the eye blinking or eye motion has finished.