	US 11,925,672 B2
	Peptide having antioxidant activity and composition containing same
Dae Hee Lee, Daegu (KR); Haet Nim Um, Chungcheongbuk-do (KR); Moon Kyung Jeong, Sejong-si (KR); Mi Na Hong, Chungcheongbuk-do (KR); Jung Hee Park, Gyeonggi-do (KR); Yong Hahk Park, Seoul (KR); and Byung Serk Hurh, Sejong-si (KR)
Assigned to SEMPIO FOODS COMPANY, Seoul (KR)
Appl. No. 17/266,811
Filed by SEMPIO FOODS COMPANY, Seoul (KR)
PCT Filed Aug. 8, 2019, PCT No. PCT/KR2019/009972 § 371(c)(1), (2) Date Feb. 8, 2021, PCT Pub. No. WO2020/032622, PCT Pub. Date Feb. 13, 2020.
Claims priority of application No. 10-2018-0092237 (KR), filed on Aug. 8, 2018.
Prior Publication US 2022/0175871 A1, Jun. 9, 2022
Int. Cl. A61K 38/06 (2006.01); A61K 38/05 (2006.01); A61P 39/06 (2006.01)

CPC A61K 38/06 (2013.01) [A61K 38/05 (2013.01); A61P 39/06 (2018.01)]

7 Claims

1. A method for treating oxidative damage to cells in a subject in need thereof, wherein the method comprises orally administering to the subject at least one peptide selected from the group consisting of (i) the amino acid sequence γ-Glu-Xaa¹or γ-Glu-Xaa²-Xaa³, and (ii) the amino acid sequence γ-Glu-Gln-Glu;

wherein

Xaa¹is any one amino acid selected from histidine (H), glutamine (Q), or isoleucine (I);

Xaa²is any one amino acid selected from threonine (T) or valine (V), and

wherein when Xaa²is threonine (T), Xaa³is glycine (G),

wherein when Xaa²is valine (V), Xaa³is any one amino acid selected from cysteine (C), aspartic acid (D), glutamic acid (E), phenylalanine (F), methionine (M), asparagine (N), proline (P), glutamine (Q), and arginine (R); and

wherein the subject is human or animal.