US 11,925,194 B2
Antimicrobially active mixtures
Kathrin Langer, Dassel-Hilwartshausen (DE); Margit Liebig, Stadtoldendorf (DE); and Johannes Kiefl, Holzminden (DE)
Assigned to SYMRISE AG, Holzminden (DE)
Appl. No. 16/762,957
Filed by SYMRISE AG, Holzminden (DE)
PCT Filed Nov. 14, 2017, PCT No. PCT/EP2017/079115
§ 371(c)(1), (2) Date May 11, 2020,
PCT Pub. No. WO2019/096363, PCT Pub. Date May 23, 2019.
Prior Publication US 2020/0397026 A1, Dec. 24, 2020
Int. Cl. A23L 3/3472 (2006.01); A23L 27/00 (2016.01); A23L 27/10 (2016.01); A23L 27/20 (2016.01); A61K 36/45 (2006.01); A61K 36/73 (2006.01); A61K 36/87 (2006.01)
CPC A23L 3/3472 (2013.01) [A23L 27/10 (2016.08); A23L 27/2028 (2016.08); A23L 27/2052 (2016.08); A23L 27/84 (2016.08); A23L 27/88 (2016.08); A61K 36/45 (2013.01); A61K 36/73 (2013.01); A61K 36/87 (2013.01)] 17 Claims
 
1. A method for prolonging the durability of a perishable foodstuff by inhibiting growth of S. cerevisiae, Z. bailii, A. pullulans, A. brasiliensis, or a combination thereof, the method comprising:
(I) adding to a foodstuff susceptible to microbial growth of S. cerevisiae, Z. bailii, A. pullulans, A. brasiliensis, or a combination thereof, a synergistically effective amount of an antimicrobial mixture, the antimicrobial mixture comprising:
(a) an extract from peels of Punica granatum comprising one or more compounds selected from catechins, chlorogenic acid, p-coumaric acid, epicatechin, ellagic acid, gallic acid, caffeic acid, sinapinic acid, and cinnamic acid, or combinations thereof; and
(b) lemon oil comprising limonene; and
(II) synergistically inhibiting the microbial growth of the S. cerevisiae, Z. bailii, A. pullulans, A. brasiliensis, or combination thereof, and prolonging the durability of the perishable foodstuff,
wherein the antimicrobial mixture of (a) and (b) is synergistically effective against the S. cerevisiae, Z. bailii, A. pullulans, A. brasiliensis, or combination thereof, compared to the individual activity of (a) and the individual activity of (b).