US 12,249,499 B2
Imaging mass spectrometer
Shinichi Yamaguchi, Kyoto (JP)
Assigned to SHIMADZU CORPORATION, Kyoto (JP)
Appl. No. 17/439,998
Filed by SHIMADZU CORPORATION, Kyoto (JP)
PCT Filed Apr. 24, 2019, PCT No. PCT/JP2019/017369
§ 371(c)(1), (2) Date Sep. 16, 2021,
PCT Pub. No. WO2020/217334, PCT Pub. Date Oct. 29, 2020.
Prior Publication US 2022/0172937 A1, Jun. 2, 2022
Int. Cl. H01J 49/00 (2006.01)
CPC H01J 49/0004 (2013.01) [H01J 49/0036 (2013.01)] 6 Claims
OG exemplary drawing
 
1. An imaging mass spectrometer comprising:
an analysis executing section configured to execute MSn analysis (n is an integer greater than or equal to 2) for a target component on each of a plurality of micro regions set within a two-dimensional measurement region on a sample or a three-dimensional measurement region in the sample to collect data;
an ion selecting section configured to select a plurality of kinds of product ions which are known to be derived from the target component or presumed to be derived from the target component based on a comparison of a compositional formula of the target component or a precursor ion in an MSn analysis and a compositional formula of the product detected in the MSn analysis based on at least a part of the data collected by the analysis executing section; and
a distribution image creating section configured to determine, using signal strength of each of the plurality of kinds of product ions in each micro region within the measurement region, a small region in which all of the plurality of kinds of product ions are detected or a small region assumed to have high reliability that all of the plurality of kinds of product ions are derived from the target component, and configured to create a distribution image visualizing the small region.