US 12,249,009 B2
Motion compensation of positron emission tomographic data
Alan Miranda, Antwerp (BE); and Jeroen Verhaeghe, Antwerp (BE)
Assigned to UNIVERSITEIT ANTWERPEN, Antwerp (BE)
Appl. No. 17/779,601
Filed by UNIVERSITEIT ANTWERPEN, Antwerp (BE)
PCT Filed Nov. 23, 2020, PCT No. PCT/EP2020/083050
§ 371(c)(1), (2) Date May 25, 2022,
PCT Pub. No. WO2021/105056, PCT Pub. Date Jun. 3, 2021.
Claims priority of application No. 19211752 (EP), filed on Nov. 27, 2019.
Prior Publication US 2023/0008263 A1, Jan. 12, 2023
Int. Cl. G06T 11/00 (2006.01); A61B 6/03 (2006.01); G01T 1/29 (2006.01)
CPC G06T 11/008 (2013.01) [A61B 6/037 (2013.01); G01T 1/2985 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A method for compensating motion in positron emission tomographic, PET, data comprising coincident lines of response from positron-emitting position markers, the method comprising:
detecting a slippage of one or more of the position markers;
deriving a plurality of images from the PET data, and, identifying therefrom, based on the detected slippage, a first set of images before the detected slippage and a second set of images after the detected slippage;
motion correcting the first and second set of images, thereby obtaining a first and a second motion-compensated set of images;
determining slippage correction parameters based on the first and second motion-compensated set of images;
applying motion correction to the PET data by taking into account the slippage correction parameters, thereby obtaining a motion-compensated PET data;
correcting scatter in the motioned-compensated PET data;
masking the position markers in the motion-compensated PET data, thereby deriving motion-compensated and masked PET data; and
deriving a PET scatter sinogram from the motion-compensated and masked PET data and scaling the PET scatter sinogram, thereby obtaining scatter corrected and motion-compensated PET data.