US 12,247,921 B2
Systems and methods for multicolor imaging
Fedor Trintchouk, San Diego, CA (US); and Eli N. Glezer, Del Mar, CA (US)
Assigned to Singular Genomics Systems, Inc., San Diego, CA (US)
Filed by Singular Genomics Systems, Inc., San Diego, CA (US)
Filed on May 10, 2023, as Appl. No. 18/315,427.
Application 18/315,427 is a continuation of application No. 17/853,449, filed on Jun. 29, 2022, granted, now 11,686,681.
Application 17/853,449 is a continuation of application No. 17/703,720, filed on Mar. 24, 2022, granted, now 11,415,515, issued on Aug. 16, 2022.
Application 17/703,720 is a continuation of application No. PCT/US2021/064423, filed on Dec. 20, 2021.
Claims priority of provisional application 63/128,477, filed on Dec. 21, 2020.
Prior Publication US 2023/0280274 A1, Sep. 7, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 21/64 (2006.01); G02B 21/08 (2006.01); G02B 21/16 (2006.01); G02B 21/18 (2006.01); G02B 21/26 (2006.01); G02B 27/10 (2006.01); H04N 23/16 (2023.01); H04N 23/45 (2023.01); H04N 23/56 (2023.01); H04N 23/84 (2023.01)
CPC G01N 21/6456 (2013.01) [G01N 21/6428 (2013.01); G02B 21/082 (2013.01); G02B 21/16 (2013.01); G02B 21/18 (2013.01); G02B 21/26 (2013.01); G02B 27/1013 (2013.01); H04N 23/16 (2023.01); H04N 23/45 (2023.01); H04N 23/56 (2023.01); H04N 23/84 (2023.01); G01N 2201/103 (2013.01)] 22 Claims
OG exemplary drawing
 
1. A method of imaging a sample on a sample stage, the method comprising:
moving the sample stage at a sample stage speed;
directing a first excitation beam onto a first location of the sample and detecting a first light emission from the sample with a first sensor array; and
directing a second excitation beam onto a second location of the sample and detecting a second light emission from the sample with a second sensor array;
wherein the first sensor array, the second sensor array, or both the first and the second sensor arrays are configured to generate a charge that transfers across the sensor array at a charge speed associated with the sample stage speed.