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1. An oligonucleotide primer, comprising, from 5′ to 3′, a 5′ primer tag sequence (PTS) covalently bonded to a 5′ residue of a homopolymer-hybridizing region, wherein the PTS consists of a linker and/or one or more nucleic acid sequences useful in nucleic acid sequence manipulation selected from: a sequencing site, a PCR site, and a hybridization site; the homopolymer-hybridizing region, and an anchor region comprising 5′-(λ)nNm-3′, wherein the homopolymer-hybridizing region hybridizes to a complementary homopolymer tract of a target nucleic acid, wherein the complementary homopolymer tract comprises a contiguous sequence of complementary elements, wherein the homopolymer-hybridizing region, and the anchor region together have a sequence selected from the group consisting of: SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, and SEQ ID NO: 15, and wherein λ is any nucleotide or nucleotide analog with the proviso that k is not a nucleotide or nucleotide analog complementary to a complementary element of the complementary homopolymer tract, and wherein N is any nucleotide or nucleotide analog.
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