	US 12,247,195 B2
	Microfluidic system and method of use thereof
Scott Noggle, New Rochelle, NY (US); and Stephen Chang, Poway, CA (US)
Assigned to New York Stem Cell Foundation, Inc., New York, NY (US)
Filed by New York Stem Cell Foundation, Inc., New York, NY (US)
Filed on Nov. 15, 2022, as Appl. No. 17/987,073.
Application 17/987,073 is a continuation of application No. 16/462,047, granted, now 11,542,465, previously published as PCT/US2017/062344, filed on Nov. 17, 2017.
Claims priority of provisional application 62/424,208, filed on Nov. 18, 2016.
Prior Publication US 2023/0144965 A1, May 11, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. C12M 1/00 (2006.01); B01L 3/00 (2006.01); F16K 99/00 (2006.01); G01N 15/02 (2024.01); G01N 15/01 (2024.01); G01N 15/10 (2024.01)

CPC C12M 47/04 (2013.01) [B01L 3/5027 (2013.01); F16K 99/0003 (2013.01); G01N 15/02 (2013.01); F16K 2099/0086 (2013.01); G01N 15/01 (2024.01); G01N 2015/1006 (2013.01)]

22 Claims

1. A microfluidic system for processing a biological sample comprising:

a) one or more microfluidic units operable to process the sample, the processing comprising:

i) expanding isolated cells to produce a population of expanded cells;

ii) reprogramming the isolated cells or the expanded cells to produce a population of reprogrammed cells; and

iii) storing cells from one or more of (i) or (ii); and

b) one or more computer memory modules containing instructions, and programmed for controlling one or more of processes (i)-(iii); and

c) one or more computer processor modules programmed to execute the instructions,

wherein the one or more microfluidic units comprises a plurality of flow channels.