US 12,246,297 B2
Edge chip
Johnathan Charles Sharpe, Hamilton (NZ); and Donald Francis Perrault, Jr., Brighton, MA (US)
Assigned to CYTONOME/ST, LLC, Lexington, MA (US)
Filed by CYTONOME/ST, LLC, Bedford, MA (US)
Filed on Mar. 13, 2023, as Appl. No. 18/120,694.
Application 18/120,694 is a continuation of application No. 17/018,760, filed on Sep. 11, 2020, granted, now 11,617,999.
Claims priority of provisional application 62/899,469, filed on Sep. 12, 2019.
Prior Publication US 2023/0211310 A1, Jul. 6, 2023
Int. Cl. B01J 19/00 (2006.01); B01L 3/00 (2006.01); G01N 15/1404 (2024.01)
CPC B01J 19/0093 (2013.01) [B01L 3/502715 (2013.01); G01N 15/1404 (2013.01); B01J 2219/00826 (2013.01); B01J 2219/00891 (2013.01); B01J 2219/00934 (2013.01); B01J 2219/0097 (2013.01); B01L 2300/08 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A particle processing system comprising:
a particle processing chip including:
a substrate having a plurality of side surfaces, a top surface, and a bottom surface, the plurality of side surfaces defining a thickness of the substrate and the top surface and the bottom surface defining a width and a length of the substrate;
a microfluidic channel disposed in the substrate parallel to a first side surface of the plurality of side surfaces and located in the substrate relative to the first side surface; and
an interrogation region of the microfluidic channel located proximate to the first side surface of the plurality of side surfaces to allow detection of light along a first optical axis extending from the first side surface of the plurality of side surfaces and detection of light along a second optical axis extending from the top surface or the bottom surface of the substrate;
an electromagnetic radiation source to illuminate the interrogation region in the microfluidic channel; and
a plurality of detectors positioned relative to the substrate to receive light from the interrogation region along the first and second optical axes.