US 12,246,267 B2
Method of capturing and/or purifying a target
Zi Ying Zheng, Singapore (SG); and Wei Zhang, Singapore (SG)
Assigned to Agency For Science, Technology and Research, Singapore (SG)
Appl. No. 17/440,374
Filed by Agency for Science, Technology and Research, Singapore (SG)
PCT Filed Mar. 20, 2020, PCT No. PCT/SG2020/050150
§ 371(c)(1), (2) Date Sep. 17, 2021,
PCT Pub. No. WO2020/190216, PCT Pub. Date Sep. 24, 2020.
Claims priority of application No. 10201902549Y (SG), filed on Mar. 21, 2019.
Prior Publication US 2022/0184526 A1, Jun. 16, 2022
Int. Cl. B01D 15/18 (2006.01); B01D 15/36 (2006.01); B01D 15/38 (2006.01); C07K 1/36 (2006.01); G01N 30/20 (2006.01)
CPC B01D 15/1864 (2013.01) [B01D 15/363 (2013.01); B01D 15/3804 (2013.01); C07K 1/36 (2013.01); G01N 30/20 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A chromatography system consisting of two valves, wherein:
a first valve is in fluid connection to a first chromatography column and/or a second valve;
the second valve is in fluid connection to a second chromatography column and the first valve;
wherein the first valve and the second valve are operable to provide:
i) a mode A that selectively allows a fluid to flow from the first chromatography column to the second chromatography column;
ii) a mode B that selectively allows the fluid to bypass the first chromatography column; and/or
iii) a mode C that selectively allows the fluid to bypass the second chromatography column,
wherein the first valve is positioned parallel to the first chromatography column; and
wherein the first valve is an injection valve, optionally the second valve is a column valve.