US 12,246,126 B2
Powder spray dispenser for comminuted ECM
Christopher Fecteau, Lafayette, IN (US)
Assigned to Cook Biotech Incorporated, West Lafayette, IN (US)
Filed by Cook Biotech Incorporated, West Lafayette, IN (US)
Filed on Feb. 28, 2020, as Appl. No. 16/804,839.
Claims priority of provisional application 62/812,192, filed on Feb. 28, 2019.
Prior Publication US 2020/0276399 A1, Sep. 3, 2020
Int. Cl. A61M 11/00 (2006.01); A61K 9/14 (2006.01); A61L 2/20 (2006.01); A61L 27/36 (2006.01); B05B 11/04 (2006.01); B65B 55/02 (2006.01)
CPC A61M 11/008 (2014.02) [A61K 9/14 (2013.01); A61L 2/206 (2013.01); A61L 27/3633 (2013.01); B05B 11/041 (2013.01); B65B 55/02 (2013.01); A61L 2202/181 (2013.01); A61L 2202/21 (2013.01); A61L 2430/34 (2013.01); A61M 2202/064 (2013.01); A61M 2202/095 (2013.01); A61M 2205/75 (2013.01); A61M 2207/10 (2013.01)] 23 Claims
OG exemplary drawing
 
1. An article of manufacture, comprising:
a sealed pouch having a first sterile barrier film defining an interior volume of the sealed pouch, the first sterile barrier film being permeable to humidified ethylene oxide gas;
a squeeze pump bottle received in the interior volume of the sealed pouch, the squeeze pump bottle having a bottle body impermeable to humidified ethylene oxide gas, the bottle body defining an interior chamber and a bottle opening, wherein a second sterile barrier film seals the bottle opening, the second sterile barrier film permeable to humidified ethylene oxide gas, and wherein a dry, comminuted collagenous extracellular matrix material powder is received in the interior chamber of the squeeze pump bottle; and
a cap received in the interior volume of the sealed pouch and attachable to the squeeze pump bottle to position the cap over the bottle opening after removal or puncture of the second barrier film, the cap having a dispensing spout defining a spout lumen terminating in a spout opening;
wherein amounts of the dry, comminuted collagenous extracellular matrix material powder are ejectable as a powder spray out of the spout opening by a pumping inward deflection of at least one wall portion of the squeeze pump bottle that causes a gas pressure impulse to travel from the interior chamber of the squeeze pump bottle through the spout lumen and out the spout opening.