US 12,246,082 B2
Efficient sunscreen compositions with diethylamino hydroxybenzoyl hexyl benzoate and butyl methoxydibenzoylmethane free of octocrylene
Myriam Sohn, Grenzach-Wyhlen (DE); Stanislaw Krus, Grenzach-Wyhlen (DE); Marcel Schnyder, Grenzach-Wyhlen (DE); and Stephanie Acker, Grenzach-Wyhlen (DE)
Assigned to BASF SE, Ludwigshafen am Rhein (DE)
Appl. No. 17/439,631
Filed by BASF SE, Ludwigshafen am Rhein (DE)
PCT Filed Mar. 13, 2020, PCT No. PCT/EP2020/056917
§ 371(c)(1), (2) Date Sep. 15, 2021,
PCT Pub. No. WO2020/187767, PCT Pub. Date Sep. 24, 2020.
Claims priority of application No. 19163177 (EP), filed on Mar. 15, 2019.
Prior Publication US 2022/0151898 A1, May 19, 2022
Int. Cl. A61K 8/49 (2006.01); A61K 8/35 (2006.01); A61K 8/44 (2006.01); A61Q 17/00 (2006.01); A61Q 17/04 (2006.01)
CPC A61K 8/4966 (2013.01) [A61K 8/35 (2013.01); A61K 8/445 (2013.01); A61Q 17/00 (2013.01); A61Q 17/04 (2013.01); A61K 2800/30 (2013.01); A61K 2800/5922 (2013.01)] 20 Claims
 
1. A sunscreen or daily care composition comprising
(i) hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate); and
(ii) 1-(4-(1,1-dimethylethyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-dione (INCI butyl methoxydibenzoylmethane); and
(iii) 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5 triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine); and
(iv) 4,4′,4″-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI ethylhexyl triazone) and/or 4,4′-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazin-2,4-diyl]diimino]bis-benzoic acid-bis(2-ethylhexyl)ester (INCI diethylhexyl-butamidotriazone); and
(v) at least one organic particulate UV filter,
wherein the composition is free of ethylhexyl-2-cyano-3,3-diphenyl-acrylate (INCI octocrylene), 2-ethylhexyl-(2E)-3-(4-methoxyphenyl)acrylate (INCI ethylhexyl methoxy cinnamate) and benzylidene malonates according to the following structures:

OG Complex Work Unit Chemistry
wherein
R1 is methyl, ethyl, propyl or n-butyl;
if R1 is methyl, then
R is tert butyl or a radical of formula

OG Complex Work Unit Chemistry
or a radical of formula

OG Complex Work Unit Chemistry
wherein
R2 and R3 are independently from each other hydrogen or methyl;
R4 is methyl, ethyl or n-propyl;
R5 and R6 are independently from each other hydrogen or C1-C3-alkyl;
if R1 is ethyl, propyl or n-butyl, then
R is isopropyl;
and wherein the composition comprises (i) to (ii) in a ratio of larger or equal to 0.8.