	US 12,246,060 B2
	Irisin improves placental function during pregnancy
Sascha Drewlo, Grand Rapids, MI (US); Hamid-Reza Kohan-Ghadr, Kentwood, MI (US); and Eugenia Johnson, East Lansing, MI (US)
Assigned to Board of Trustees of Michigan State University, East Lansing, MI (US)
Appl. No. 17/439,163
Filed by Board of Trustees of Michigan State University, East Lansing, MI (US)
PCT Filed Mar. 13, 2020, PCT No. PCT/US2020/022733 § 371(c)(1), (2) Date Sep. 14, 2021, PCT Pub. No. WO2020/190759, PCT Pub. Date Sep. 24, 2020.
Claims priority of provisional application 62/819,239, filed on Mar. 15, 2019.
Prior Publication US 2022/0152158 A1, May 19, 2022
Int. Cl. A61K 38/17 (2006.01); A61K 9/00 (2006.01); A61K 38/22 (2006.01); A61K 45/06 (2006.01)

CPC A61K 38/22 (2013.01) [A61K 9/0019 (2013.01); A61K 38/1709 (2013.01); A61K 45/06 (2013.01)]

19 Claims

1. A method of treating a subject having a placental dysfunction, the method comprising:

administering to the subject a therapeutically effective amount of a composition comprising irisin.