US 12,245,894 B2
System and method for non-invasive real time assessment of cardiovascular blood pressure
Alexander Brenner, Haifa (IL); Felix Brenner, Haifa (IL); and Avraham Lorber, Haifa (IL)
Assigned to Pi-Harvest Holding AG, Schaffhausen (CH)
Filed by Alexander Brenner, Haifa (IL); Felix Brenner, Haifa (IL); and Avraham Lorber, Haifa (IL)
Filed on Feb. 21, 2020, as Appl. No. 16/797,357.
Prior Publication US 2021/0259666 A1, Aug. 26, 2021
Int. Cl. A61B 8/08 (2006.01); A61B 5/021 (2006.01); A61B 6/50 (2024.01); A61B 8/00 (2006.01); A61B 8/04 (2006.01); G06T 7/00 (2017.01)
CPC A61B 8/5223 (2013.01) [A61B 8/04 (2013.01); A61B 8/54 (2013.01); A61B 8/56 (2013.01); G06T 7/0012 (2013.01); A61B 5/021 (2013.01); A61B 6/507 (2013.01); G06T 2207/30048 (2013.01)] 2 Claims
OG exemplary drawing
 
1. A system for non-invasive measurement of intracardiac pressure comprising:
a medical imaging device capable of highlighting cardiovascular structures, including heart chambers and blood vessels connected to the heart of a user, and
a processor unit equipped with software configured to calculate dynamically changing intracardiac pressures of the user;
wherein the system is assembled and prepared by the user or an external operator, which:
connects the medical imaging device to the processor unit,
activates and points the medical imaging device towards the user's cardiac region;
wherein the assembled system is further controlled by the user or the external operator by activating the processor unit, which:
synchronizes the medical imaging device with the processor unit,
receives an image stream {Ji}i=1, . . . N from the medical imaging device,
stores the image stream and generates a corresponding T-image {Ti}i=1, . . . N, which is defined as chronological union of the image stream {Ji}i=1, . . . N with corresponding timestamps,
following the creation of the T-image {Ti}i=1, . . . N from the imaging data obtained from the medical imaging device, the processor unit further
identifies a set of coordinate parameters {xj}j=1, . . . Mi (where i is an index of the image, j is an index of the coordinate parameter and M is the total number of the coordinate parameters) representing an oscillating traceable region size and position on each frame Ti of the T-image {Ti}i=1, . . . N, by means of image processing,
estimates the size, shape and positions of the target oscillating traceable region(s) from each frame of the T-image {Ti}i=1, . . . N, based on the obtained set of coordinate parameters {xj}j=1, . . . Mi,
estimates pressure values Pi iterating from frame to frame of T-image {Ti}i=1, . . . N, based on the change in the size and position of the oscillating traceable region(s),
stores on local computer medium or transmits via connection to a server, the T-Image, the set of coordinate parameters of the oscillating traceable region(s) and the estimated pressure values Pi,
displays the series of pressure values Pi on a graphical user interface (GUI).