US 12,245,802 B2
Generating irreversible electroporation and radiofrequency-abaltion (IRE/RFA) waveforms
Assaf Govari, Haifa (IL); and Andres Claudio Altmann, Haifa (IL)
Assigned to Biosense Webster (Israel) Ltd., Yokneam (IL)
Filed by Biosense Webster (Israel) Ltd., Yokneam (IL)
Filed on Apr. 18, 2023, as Appl. No. 18/302,109.
Application 18/302,109 is a continuation of application No. 16/704,421, filed on Dec. 5, 2019, granted, now 11,660,135.
Prior Publication US 2023/0248412 A1, Aug. 10, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 18/12 (2006.01); A61B 18/00 (2006.01); A61N 1/32 (2006.01)
CPC A61B 18/1233 (2013.01) [A61N 1/327 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00613 (2013.01); A61B 18/1206 (2013.01); A61B 2018/1266 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A system for combining irreversible electroporation and radio frequency ablation (IRE/RFA), comprising:
an IRE pulse generator configured to generate biphasic IRE square pulses;
a biphasic pulse shaper, configured and controlled by a processor, to adapt the biphasic IRE square pulses to IRE pulses having a final shape and repetition rate;
one or more harmonic filters, configured and controlled by the processor, to convert the biphasic IRE square pulses into an RF sinusoidal signal; and
a waveform interleaver comprising switching circuitry, which is configured and controlled by the processor, to receive the IRE square pulses and the converted RF sinusoidal signal and generate an output signal having a composition comprising one of: i) the adapted IRE pulses having a final shape and repetition rate, ii) the converted RF sinusoidal signal, or iii) a combined IRE/RFA output signal that switches between the adapted IRE square pulses and the converted RF sinusoidal signal.