US 11,921,067 B2
System and method for magnetic resonance mapping of physical and chemical changes in conducting structures
Alexej Jerschow, New York, NY (US); Andrew J. Ilott, Rahway, NJ (US); Mohaddese Mohammadi, Brooklyn, NY (US); Emilia Silletta, Cordoba (AR); and Konstantin Romanenko, New York, NY (US)
Assigned to New York University, New York, NY (US)
Filed by NEW YORK UNIVERSITY, New York, NY (US)
Filed on Jun. 6, 2019, as Appl. No. 16/434,168.
Application 16/434,168 is a continuation in part of application No. PCT/US2017/064948, filed on Dec. 6, 2017.
Application PCT/US2017/064948 is a continuation in part of application No. 15/785,284, filed on Oct. 16, 2017, granted, now 10,712,297.
Application 15/785,284 is a continuation in part of application No. PCT/US2016/027624, filed on Apr. 14, 2016.
Claims priority of provisional application 62/431,075, filed on Dec. 7, 2016.
Claims priority of provisional application 62/149,159, filed on Apr. 17, 2015.
Prior Publication US 2019/0310211 A1, Oct. 10, 2019
Int. Cl. G01N 24/08 (2006.01); G01N 24/10 (2006.01); G01R 31/36 (2020.01); G01R 33/56 (2006.01)
CPC G01N 24/08 (2013.01) [G01N 24/10 (2013.01); G01R 31/3644 (2013.01); G01R 33/5602 (2013.01); G01R 33/5608 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A method of diagnosing a conducting structure, the method comprising:
providing the conducting structure in a magnetic field;
exciting nuclear or electronic spins within a detection medium using an electromagnetic signal having a first frequency;
receiving an electromagnetic signal having a second frequency from the detection medium;
obtaining a first distribution of frequencies of the detection medium at a first time and a second distribution of frequencies of the detection medium at a second time different from the first time, the detection medium external to the conducting structure and the first distribution of frequencies different from the second distribution of frequencies; and
detecting frequency changes between the first distribution of frequencies of the detection medium and the second distribution of frequencies of the detection medium to obtain internal characteristics of the conducting structures;
wherein the internal characteristics of the conducting structure are modeled on the basis of magnetic susceptibility differences and changes within the conducting structure, the modeling comprising:
assigning one or more regions within the conducting structure a given magnetic susceptibility; and
calculating a generated magnetic field based on an effect on the detection medium,
wherein susceptibilities of the one or more regions form parameters configured to be fit by minimizing differences between a calculated frequency distribution and a measured frequency distribution in the detection medium.