	US 11,920,196 B2
	Circulating microRNAs in knee osteoarthritis and uses thereof
Mohit Kapoor, Pickering (CA); Rajiv Gandhi, Toronto (CA); and Shabana Amanda Ali, Windsor (CA)
Assigned to University Health Network, Toronto (CA)
Filed by University Health Network, Toronto (CA)
Filed on Jun. 2, 2021, as Appl. No. 17/337,163.
Claims priority of provisional application 63/033,463, filed on Jun. 2, 2020.
Prior Publication US 2021/0381047 A1, Dec. 9, 2021
Int. Cl. C12Q 1/6876 (2018.01)

CPC C12Q 1/6876 (2013.01) [C12Q 2600/178 (2013.01)]

22 Claims

1. A method comprising:

a) obtaining a substantially cell-free sample of blood plasma or blood serum from a subject with knee osteoarthritis; and

b) detecting the presence of, and optionally measuring the level of, SEQ ID NOs: 1-4 in the sample.