	US 11,918,666 B2
	Topical formulations comprising strontium and methylsulfonylmethane (MSM) and methods of treatment
Eran Rosman, Tel Aviv (IL); and Masha Minkin, Tel Aviv (IL)
Assigned to NOON AESTHETICS M.R LTD., Tel-Aviv (IL)
Filed by NOON AESTHETICS M.R LTD., Tel-Aviv (IL)
Filed on Oct. 9, 2020, as Appl. No. 17/067,259.
Application 17/067,259 is a continuation in part of application No. PCT/IL2019/050386, filed on Apr. 4, 2019.
Claims priority of provisional application 62/654,540, filed on Apr. 9, 2018.
Prior Publication US 2021/0100725 A1, Apr. 8, 2021
Int. Cl. A61K 8/19 (2006.01); A61K 8/34 (2006.01); A61K 8/365 (2006.01); A61K 8/368 (2006.01); A61K 8/38 (2006.01); A61K 8/46 (2006.01); A61K 8/67 (2006.01); A61K 8/9789 (2017.01); A61K 31/10 (2006.01); A61K 33/14 (2006.01); A61K 33/24 (2019.01); A61Q 19/02 (2006.01); A61Q 19/08 (2006.01); A61Q 19/10 (2006.01); A61K 45/06 (2006.01)

CPC A61K 8/19 (2013.01) [A61K 8/347 (2013.01); A61K 8/365 (2013.01); A61K 8/368 (2013.01); A61K 8/38 (2013.01); A61K 8/463 (2013.01); A61K 8/466 (2013.01); A61K 8/671 (2013.01); A61K 8/9789 (2017.08); A61K 31/10 (2013.01); A61K 33/14 (2013.01); A61K 33/24 (2013.01); A61Q 19/02 (2013.01); A61Q 19/08 (2013.01); A61Q 19/10 (2013.01); A61K 45/06 (2013.01); A61K 2800/10 (2013.01); A61K 2800/75 (2013.01)]

18 Claims

1. A topical composition comprising a combination of: a strontium salt selected from the group consisting of strontium chloride, strontium acetate, strontium nitrate and strontium chloride hexahydrate; methylsulfonylmethane; and a physiologically acceptable carrier, wherein the strontium salt:MSM concentration ratio is in the range of from 5%:10% to 10%:5% w/w.