US 11,918,349 B2
Model predictive control for diabetes management
Garry M. Steil, Boston, MA (US); Sami S. Kanderian, Jr., Germantown, MD (US); Martin T. Cantwell, Canyon Country, CA (US); and Udo Hoss, Sherman Oaks, CA (US)
Assigned to MEDTRONIC MINIMED, INC., Northridge, CA (US)
Filed by MEDTRONIC MINIMED, INC., Northridge, CA (US)
Filed on Oct. 29, 2020, as Appl. No. 17/084,474.
Application 17/084,474 is a continuation of application No. 16/154,997, filed on Oct. 9, 2018, granted, now 10,856,786.
Application 16/154,997 is a continuation of application No. 11/700,666, filed on Jan. 31, 2007, granted, now 10,154,804, issued on Dec. 18, 2018.
Prior Publication US 2021/0038134 A1, Feb. 11, 2021
Int. Cl. A61B 5/145 (2006.01); A61B 5/00 (2006.01); A61B 5/1486 (2006.01); A61B 5/1495 (2006.01); A61K 38/28 (2006.01); A61M 5/142 (2006.01); A61M 5/158 (2006.01); A61M 5/172 (2006.01); G16H 20/10 (2018.01); G16H 20/17 (2018.01); G16Z 99/00 (2019.01)
CPC A61B 5/14532 (2013.01) [A61B 5/14865 (2013.01); A61B 5/4839 (2013.01); A61B 5/6849 (2013.01); A61B 5/7275 (2013.01); A61K 38/28 (2013.01); A61M 5/14244 (2013.01); A61M 5/1723 (2013.01); C12Y 301/01003 (2013.01); G16H 20/17 (2018.01); G16Z 99/00 (2019.02); A61B 5/1495 (2013.01); A61M 2005/14208 (2013.01); A61M 5/158 (2013.01); A61M 2005/1581 (2013.01); A61M 5/1582 (2013.01); A61M 2205/3523 (2013.01); A61M 2205/3561 (2013.01); A61M 2205/3569 (2013.01); G16H 20/10 (2018.01)] 20 Claims
OG exemplary drawing
 
1. A processor-implemented method comprising:
obtaining a current glucose value for a user of an insulin delivery device;
generating a desired glucose trajectory that approaches a desired steady state setpoint from the current glucose value over a prediction horizon;
generating an insulin delivery pattern corresponding to an amount of insulin to be delivered to the user over a control horizon;
generating a predicted glucose trajectory over the control horizon, the predicted glucose trajectory being generated based on the current glucose value and the insulin delivery pattern;
comparing the desired glucose trajectory against the predicted glucose trajectory;
responsive to a difference between the desired glucose trajectory and the predicted glucose trajectory being no larger than a predetermined threshold, selecting the predicted glucose trajectory, wherein the difference is determined based on a cost function;
determining the insulin delivery pattern used to generate the predicted glucose trajectory; and
causing insulin delivery by the insulin delivery device in accordance with the determined insulin delivery pattern.