US 11,918,315 B2
Determination of structure and traversal of occlusions using magnetic particles
Brian L. Kidd, Wildwood, MO (US); Sean C. Morris, Wildwood, MO (US); and Michael E. Sabo, Prairie du Rocher, IL (US)
Assigned to Pulse Therapeutics, Inc., St. Louis, MO (US)
Filed by Pulse Therapeutics, Inc., St. Louis, MO (US)
Filed on May 2, 2019, as Appl. No. 16/401,786.
Claims priority of provisional application 62/666,639, filed on May 3, 2018.
Prior Publication US 2019/0336231 A1, Nov. 7, 2019
Int. Cl. A61B 34/00 (2016.01); A61K 41/00 (2020.01); A61K 49/06 (2006.01); A61B 90/00 (2016.01)
CPC A61B 34/73 (2016.02) [A61K 41/00 (2013.01); A61K 49/06 (2013.01); A61B 2090/374 (2016.02); A61B 2090/3762 (2016.02); A61B 2090/378 (2016.02)] 20 Claims
OG exemplary drawing
 
1. A method of facilitating treatment of a therapeutic target within a body of a subject, the method comprising:
delivering magnetic particles to a location near the therapeutic target within the body of the subject;
applying a rotating magnetic field so as to cause the magnetic particles to agglomerate into stir bars and to generate a circulating motion adjacent the therapeutic target so as to cause at least some of the magnetic particles to be driven into an outer surface of the therapeutic target;
obtaining images indicative of a shape of a profile or face outline of the outer surface of the therapeutic target using an imaging modality capable of imaging the magnetic particles;
determining the shape of the profile or face outline of the outer surface of the therapeutic target based on the images; and
selecting a particular instrument to penetrate or traverse through the therapeutic target based on the determined shape of the profile or face outline of the outer surface of the therapeutic target.