US 11,918,011 B2
High-payload, non-porous, enzyme-containing coated granules and use of same
Samuel A. Maurer, Palo Alto, CA (US); Nathaniel T. Becker, Palo Alto, CA (US); Douglas A. Dale, Palo Alto, CA (US); Peyman Moslemy, Palo Alto, CA (US); Michael Reichman, Palo Alto, CA (US); and Alan Martin Allgeier, Palo Alto, CA (US)
Assigned to DANISCO US INC., Palo Alto, CA (US)
Appl. No. 15/734,065
Filed by DANISCO US INC, Palo Alto, CA (US)
PCT Filed May 30, 2019, PCT No. PCT/US2019/034503
§ 371(c)(1), (2) Date Dec. 1, 2020,
PCT Pub. No. WO2019/232119, PCT Pub. Date Dec. 5, 2019.
Claims priority of provisional application 62/679,415, filed on Jun. 1, 2018.
Prior Publication US 2021/0219574 A1, Jul. 22, 2021
Int. Cl. A23K 20/189 (2016.01); A23K 20/22 (2016.01); A23K 40/10 (2016.01); A23K 40/30 (2016.01); C12N 9/16 (2006.01); C12N 9/96 (2006.01)
CPC A23K 20/189 (2016.05) [A23K 20/22 (2016.05); A23K 40/10 (2016.05); A23K 40/30 (2016.05); C12N 9/16 (2013.01); C12N 9/96 (2013.01); C12Y 301/03 (2013.01)] 50 Claims
OG exemplary drawing
 
1. An enzyme-containing coated granule comprising:
(a) a payload of at least 10% wt/wt enzyme solids;
(b) a continuous protective coating surrounding an enzyme matrix core resulting in a coated granule having
(i) a porosity of less than about 0.03 cc/g for macropores within the range of 0.2-8.0 microns in diameter; and
(ii) a water uptake of no more than 0.5% w/w water at 60% relative humidity.