| CPC H01S 3/0014 (2013.01) [G01J 3/0205 (2013.01); G01J 3/0218 (2013.01); G01J 3/027 (2013.01); G01J 3/44 (2013.01); H01S 3/005 (2013.01)] | 18 Claims |

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1. A laser device for use with a scientific instrument, the laser device comprising:
a laser emitter configured to generate a laser beam for radiating a sample disposed in a vacuum chamber of the scientific instrument; and
a control system configured to receive a pressure signal associated with the vacuum chamber from a pressure sensor, and to change a state of the laser beam in response to the pressure reaching a threshold level,
wherein the scientific instrument is a charged particle microscope.
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