	US 12,241,886 B2
	Transmembrane nanopore with nucleic acid unwinding function and its construction methods and applications
Jia Geng, Chengdu (CN); and Yuquan Wei, Chengdu (CN)
Assigned to Guangzhou Kongque Gene Technology Co. LTD., Guangzhou (CN)
Appl. No. 16/480,209
Filed by Guangzhou Kongque Gene Technology Co. LTD., Guangzhou (CN)
PCT Filed Jan. 23, 2018, PCT No. PCT/CN2018/073716 § 371(c)(1), (2) Date Jul. 23, 2019, PCT Pub. No. WO2018/137592, PCT Pub. Date Aug. 2, 2018.
Claims priority of application No. 201710060033.9 (CN), filed on Jan. 24, 2017.
Prior Publication US 2019/0383790 A1, Dec. 19, 2019
Int. Cl. C12N 9/14 (2006.01); A61K 9/70 (2006.01); A61K 47/42 (2017.01); C07K 14/00 (2006.01); C12N 15/37 (2006.01); C12N 15/55 (2006.01); C12Q 1/6869 (2018.01); G01N 33/487 (2006.01); B82Y 5/00 (2011.01)

CPC G01N 33/48721 (2013.01) [A61K 9/7007 (2013.01); A61K 47/42 (2013.01); C07K 14/00 (2013.01); C12N 9/14 (2013.01); C12Q 1/6869 (2013.01); B82Y 5/00 (2013.01); C12N 2710/20022 (2013.01); C12Q 2565/631 (2013.01); C12Y 306/04012 (2013.01); G01N 2333/914 (2013.01)]

13 Claims

1. A protein having an ability to form a multimeric protein pore having helicase activity, wherein the protein comprises the amino acid sequence of SEQ ID NO: 7.