| CPC A61M 16/024 (2017.08) [A61M 16/0003 (2014.02); A61M 16/0051 (2013.01); A61M 16/0069 (2014.02); A61M 16/06 (2013.01); A61M 2016/0027 (2013.01); A61M 2016/0033 (2013.01); A61M 16/0084 (2014.02); A61M 16/01 (2013.01); A61M 16/12 (2013.01); A61M 2202/0208 (2013.01); A61M 2205/15 (2013.01); A61M 2205/50 (2013.01); A61M 2205/505 (2013.01); A61M 2230/42 (2013.01)] | 15 Claims |

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1. A ventilation system comprising:
a mask assembly comprising:
a mask body having an inner surface configured for engagement with a face of a subject and an outer surface opposite the inner surface; and
a pressure sensor remote from, and operatively associated with, the mask body and configured to measure pressure within the mask,
wherein the mask body defines an inlet opening and a plurality of leak openings extending between the inner and outer surfaces of the mask body;
a blowing assembly positioned in fluid communication with the inlet opening of the mask body and configured to direct air to the inlet opening of the mask; and
a processor positioned in operative communication with the blowing assembly and the pressure sensor of the mask, wherein the processor is configured to selectively control and dynamically adjust a blower speed of the blowing assembly based upon at least the measured pressure within the mask in order to maintain at least one of a desired pressure within the mask and a tidal volume for each breath of the subject above a predetermined value, and
wherein the ventilation system further comprises:
a first flow sensor that is positioned in communication with the processor and configured to measure an air flow rate at which air is provided from the blowing assembly to the inlet opening of the mask body; and
a second flow sensor that is positioned in operative communication with the processor and configured to measure an oxygen flow rate at which oxygen is provided from an oxygen source in fluid communication with the inlet opening of the mask body and positioned in operative communication with the processor, and wherein the processor is further configured to:
automatically calculate a fraction of inspired oxygen (FiO2) value based upon the measured air and measured oxygen flow rates; and
cause the oxygen source to provide a supply of oxygen to the mask from the oxygen source based upon one or more measured conditions, wherein the oxygen flow rate is manually adjusted by the clinician using the FiO2.
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