David Turer, Pittsburgh, PA (US); William W. Clark, Wexford, PA (US); April Lawrence, Pittsburgh, PA (US); Ehsan Qaium, Pittsburgh, PA (US); Joseph P. Rubin, Pittsburgh, PA (US); and Cameron Dezfulian, Pittsburgh, PA (US)
Assigned to University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US); and UPMC, Pittsburgh, PA (US)
Filed by University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US); and UPMC, Pittsburgh, PA (US)
Filed on Jan. 3, 2023, as Appl. No. 18/149,394.
Application 18/149,394 is a continuation of application No. 17/050,504, granted, now 11,547,787, previously published as PCT/US2019/031815, filed on May 10, 2019.
Claims priority of provisional application 62/736,813, filed on Sep. 26, 2018.
Claims priority of provisional application 62/697,596, filed on Jul. 13, 2018.
Claims priority of provisional application 62/669,781, filed on May 10, 2018.
Prior Publication US 2023/0149620 A1, May 18, 2023
1. A device comprising a metal cannula with two electrodes at or near a tip of the cannula operable to measure impedance of tissue adjacent to the tip of the cannula, wherein the cannula is operable as a first electrode of the two electrodes and a removable sheath positionable over the cannula comprises a second electrode of the two electrodes, the removable sheath further comprising an electrical insulation layer between the cannula and the second electrode that electrically insulates the cannula from the second electrode, wherein an impedance sensing system is electrically coupled to the cannula and electrically coupled to the second electrode to measure impedance of tissue adjacent the tip of the cannula, and wherein the removable sheath comprises a conductor that makes electrical contact with the cannula when the removable sheath is positioned over the cannula.
