US 12,239,767 B2
Dissolvable microneedle arrays for transdermal delivery to human skin
Louis D. Falo, Jr., Wexford, PA (US); Geza Erdos, Wexford, PA (US); and O. Burak Ozdoganlar, Sewickley, PA (US)
Assigned to University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US); and Carnegie Mellon University, Pittsburgh, PA (US)
Filed by University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US); and Carnegie Mellon University, Pittsburgh, PA (US)
Filed on Aug. 23, 2023, as Appl. No. 18/454,628.
Application 14/458,050 is a division of application No. 12/910,516, filed on Oct. 22, 2010, granted, now 8,834,423, issued on Sep. 16, 2014.
Application 18/454,628 is a continuation of application No. 16/861,112, filed on Apr. 28, 2020, granted, now 11,744,927.
Application 16/861,112 is a continuation of application No. 14/458,050, filed on Aug. 12, 2014, abandoned.
Claims priority of provisional application 61/279,623, filed on Oct. 23, 2009.
Prior Publication US 2024/0238486 A1, Jul. 18, 2024
Int. Cl. A61M 37/00 (2006.01); A61L 31/04 (2006.01); A61L 31/06 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01); B23C 3/00 (2006.01)
CPC A61L 31/148 (2013.01) [A61L 31/042 (2013.01); A61L 31/06 (2013.01); A61L 31/16 (2013.01); A61M 37/0015 (2013.01); B23C 3/00 (2013.01); A61L 2300/426 (2013.01); A61L 2300/604 (2013.01); A61L 2400/06 (2013.01); A61M 2037/0053 (2013.01); B23C 2215/00 (2013.01); B23C 2220/48 (2013.01); B23C 2226/00 (2013.01); Y10T 409/303752 (2015.01)] 16 Claims
OG exemplary drawing
 
1. A dissolvable microneedle array comprising:
a base portion; and
a plurality of microneedles, the microneedles extending from a surface of the base portion and being pre-formed to have a pillar shape,
wherein the microneedles comprise a dissoluble biocompatible material, and
wherein the microneedles comprise a bioactive agent.