	US 12,239,744 B2
	Surfactant peptide nanostructures and uses thereof in drug delivery
Eun Seok Gil, Acton, MA (US); Elton Aleksi, West Roxbury, MA (US); and Noriaki Matsuda, Tokyo (JP)
Assigned to 3-D Matrix, Ltd., Tokyo (JP)
Filed by 3-D Matrix, Ltd., Tokyo (JP)
Filed on Apr. 17, 2022, as Appl. No. 17/722,357.
Application 17/722,357 is a continuation of application No. 16/206,319, filed on Nov. 30, 2018, granted, now 11,324,703.
Claims priority of provisional application 62/599,566, filed on Dec. 15, 2017.
Prior Publication US 2022/0249392 A1, Aug. 11, 2022
Int. Cl. A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 9/51 (2006.01); A61K 31/713 (2006.01); A61K 47/42 (2017.01); A61K 31/7105 (2006.01); A61K 45/06 (2006.01)

CPC A61K 9/5169 (2013.01) [A61K 9/0019 (2013.01); A61K 9/0092 (2013.01); A61K 9/08 (2013.01); A61K 9/5192 (2013.01); A61K 31/713 (2013.01); A61K 47/42 (2013.01); A61K 31/7105 (2013.01); A61K 45/06 (2013.01)]

6 Claims

1. A drug delivery composition, said drug delivery composition comprising a peptide that consists of the amino acid sequence of AAAK (SEQ ID NO:1), wherein the peptide is present at a concentration of at least 0.01% (w/v) in an aqueous solution that has a pH from about 6 to about 8, and wherein the peptide is complexed with an siRNA.