	US 12,239,743 B2
	Dynamic bio-nanoparticle platforms
Franco Vitaliano, Boston, MA (US); and Gordana Dragan Vitaliano, Boston, MA (US)
Assigned to METAQOR LLC, Boston, MA (US)
Filed by METAQOR LLC, Boston, MA (US)
Filed on Aug. 13, 2021, as Appl. No. 17/402,222.
Application 17/402,222 is a continuation of application No. 13/847,058, filed on Mar. 19, 2013, granted, now 11,096,901.
Application 13/847,058 is a continuation of application No. 12/399,906, filed on Mar. 6, 2009, granted, now 11,235,062.
Prior Publication US 2022/0047520 A1, Feb. 17, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 9/51 (2006.01); A61K 9/50 (2006.01)

CPC A61K 9/5169 (2013.01) [A61K 9/5068 (2013.01)]

8 Claims

1. A composition comprising: 1) a human clathrin triskelion and 2) a therapeutic and/or diagnostic agent, wherein the human clathrin triskelion consists of (i) 3 isolated clathrin heavy chain (CHC) proteins and (ii) 3 isolated clathrin light chain (CLC) proteins, wherein the human clathrin triskelion is linked to the therapeutic and/or diagnostic agent, and wherein the CHC is linked to one or more biodegradable controlled-release polymers.