	US 12,239,707 B2
	Photodynamic compositions and methods of use
Matthew T. McLeay, Omaha, NE (US)
Assigned to MT RESEARCH, LLC, San Diego, CA (US)
Appl. No. 17/054,087
Filed by MT RESEARCH, LLC, San Diego, CA (US)
PCT Filed May 7, 2019, PCT No. PCT/US2019/031106 § 371(c)(1), (2) Date Nov. 9, 2020, PCT Pub. No. WO2019/217413, PCT Pub. Date Nov. 14, 2019.
Claims priority of provisional application 62/668,199, filed on May 7, 2018.
Prior Publication US 2021/0299258 A1, Sep. 30, 2021
Int. Cl. A61K 41/00 (2020.01); A61K 9/00 (2006.01); A61P 35/04 (2006.01)

CPC A61K 41/0071 (2013.01) [A61K 9/0019 (2013.01); A61P 35/04 (2018.01)]

10 Claims

1. A method for treating a tumor consisting of:

a. administering to a patient in need thereof a photosensitizer, selected from the group consisting of nintedanib, photofrin, talaporfin, hexaminolevulinate, aminolevulinic acid, and verteporfin;

b. administering to said patient oxygenated perflubron; and

c. delivering sound waves to the tumor to affect the generation of reactive oxygen species.