US 12,239,703 B2
Composite-type nano-vaccine particle
Chung Chin Sun, Richmond (CA); and Dean Mo Liu, Surrey (CA)
Assigned to Nuecology Biomedical Inc., Richmond (CA)
Filed by NEUCOLOGY BIOMEDICAL INC., Richmond (CA)
Filed on May 11, 2022, as Appl. No. 17/662,969.
Claims priority of provisional application 63/193,253, filed on May 26, 2021.
Prior Publication US 2022/0378905 A1, Dec. 1, 2022
Int. Cl. A61K 39/215 (2006.01); A61K 39/00 (2006.01)
CPC A61K 39/215 (2013.01) [A61K 2039/55505 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/6087 (2013.01)] 10 Claims
OG exemplary drawing
 
1. A nano-vaccine particle, comprising:
an amphiphilic carrier;
an active ingredient; and
at least one adjuvant,
wherein the nano-vaccine particle shows a negatively-charged surface, and
wherein the amphiphilic carrier encapsulates the active ingredient and the adjuvant,
wherein the active ingredient is a spike receptor-binding domain protein of SARS-CoV-2, and
wherein an amino acid sequence of the spike receptor-binding domain protein is set forth by SEQ ID NO:1.