US 12,239,659 B2
Methods of administering safe colon cleansing compositions
Edmund V. Dennett, Walpole, MA (US); Mark Cleveland, Norwell, MA (US); Russell W. Pelham, Duxbury, MA (US); and Matthew Walker, Brighton, MA (US)
Filed by Braintree Laboratories, Inc., Braintree, MA (US)
Filed on Jun. 14, 2024, as Appl. No. 18/743,526.
Claims priority of provisional application 63/521,314, filed on Jun. 15, 2023.
Prior Publication US 2024/0415875 A1, Dec. 19, 2024
Int. Cl. A61K 33/04 (2006.01); A61K 9/08 (2006.01); A61K 31/765 (2006.01); A61K 47/02 (2006.01); A61K 47/26 (2006.01); A61P 1/10 (2006.01)
CPC A61K 31/765 (2013.01) [A61K 9/08 (2013.01); A61K 33/04 (2013.01); A61K 47/02 (2013.01); A61K 47/26 (2013.01); A61P 1/10 (2018.01)] 9 Claims
 
1. A method of cleansing a colon of a patient, the method comprising:
(a) providing a first container comprising a first portion of a first dose of a colon cleansing product comprising about 178.7 grams of polyethylene glycol, about 7.3 grams of sodium sulfate, about 1.12 grams of potassium chloride, about 0.9 grams of magnesium sulfate, 0.5 grams of sodium chloride, lemon-lime flavor, neotame, and advantame;
(b) providing a second container comprising a second portion of the first dose of a colon cleansing product comprising malic acid and citric acid;
(c) mixing the contents of the first container and the contents of the second container together to form a first mixture and then mixing the first mixture with about 0.5 liters to about 1.0 liters of water, thereby forming the first dose of the colon cleansing product;
(d) consuming the first dose;
(e) providing a third container comprising a first portion of a second dose of the colon cleansing product comprising about 178.7 grams of polyethylene glycol, about 7.3 grams of sodium sulfate, about 1.12 grams of potassium chloride, about 0.9 grams of magnesium sulfate, about 0.5 grams of sodium chloride, lemon-lime flavor, neotame, and advantame;
(f) providing a fourth container comprising a second portion of the second dose of the colon cleansing product comprising malic acid and citric acid;
(g) mixing the contents of the third container and the contents of the fourth container together to form a second mixture and then mixing the second mixture with about 0.5 liters to about 1.0 liters of water, thereby forming the second dose of the colon cleansing product; and
(h) consuming the second dose, wherein consumption of the first dose and second dose cleanses the colon of the patient sufficiently for diagnostic and surgical procedures to be performed, wherein the combination of the first dose and the second dose does not cause a sodium balance of −50.00 mEq/L or greater in the patient.