US 12,239,650 B2
Compounds for treating and preventing net associated complications
Christopher Parish, Kingston (AU); Connor O'Meara, Newcastle (AU); Lucy Coupland, Chifley (AU); Benjamin Ju Chye Quah, Jerrabomberra (AU); Farzaneh Kordbacheh, Belconnen (AU); Anna Orlov, Narrabundah (AU); Anna Browne, Acton (AU); Ross Stephens, Stirling (AU); Gregory David Tredwell, Turner (AU); Lee Andrew Philip, Greenleigh (AU); Karen Knox, Ellen Grove (AU); Laurence Mark von Itzstein, Gilston (AU); Chih-Wei Chang, Upper Commera (AU); Anne Bruestle, Acton (AU); and David Anak Simon Davis, Belconnen (AU)
Assigned to The Australian National University, Acton (AU); and Griffith University, Nathan (AU)
Appl. No. 17/430,756
Filed by The Australian National University, Acton (AU); and Griffith University, Nathan (AU)
PCT Filed Feb. 25, 2019, PCT No. PCT/AU2019/050156
§ 371(c)(1), (2) Date Aug. 13, 2021,
PCT Pub. No. WO2020/172698, PCT Pub. Date Sep. 3, 2020.
Prior Publication US 2022/0168327 A1, Jun. 2, 2022
Int. Cl. A61K 31/7028 (2006.01); A61K 31/7016 (2006.01); A61P 37/06 (2006.01)
CPC A61K 31/7028 (2013.01) [A61K 31/7016 (2013.01); A61P 37/06 (2018.01)] 6 Claims
OG exemplary drawing
 
1. A method of treating acute pancreatitis, wherein the method comprises administering to a subject in need thereof, a therapeutically effective amount of a polyanionic sulfated cellobioside compound having the general structure of

OG Complex Work Unit Chemistry
wherein R1 is methoxy, and
wherein R2 to R8 are each selected from O-sulfate, or a pharmaceutically acceptable salt thereof.