US 12,239,634 B2
Methods of treating pruritus
Yael Rosen, Jerusalem (IL); David Dangoor, Jerusalem (IL); and Richard Fisher, Jerusalem (IL)
Assigned to CLEXIO BIOSCIENCES LTD., Jerusalem (IL)
Filed by Clexio Biosciences Ltd., Jerusalem (IL)
Filed on Oct. 10, 2023, as Appl. No. 18/483,615.
Application 18/483,615 is a continuation of application No. 17/516,871, filed on Nov. 2, 2021, granted, now 11,903,928.
Application 17/516,871 is a continuation of application No. 16/864,400, filed on May 1, 2020, granted, now 11,185,532, issued on Nov. 30, 2021.
Claims priority of provisional application 62/960,027, filed on Jan. 12, 2020.
Claims priority of provisional application 62/862,481, filed on Jun. 17, 2019.
Claims priority of provisional application 62/841,373, filed on May 1, 2019.
Prior Publication US 2024/0033252 A1, Feb. 1, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/4164 (2006.01); A61K 9/00 (2006.01); A61K 31/4174 (2006.01); A61K 45/06 (2006.01); A61P 17/04 (2006.01)
CPC A61K 31/4174 (2013.01) [A61K 9/0014 (2013.01); A61K 45/06 (2013.01); A61P 17/04 (2018.01)] 20 Claims
 
1. A method of treating notalgia paresthetica in a subject in need thereof comprising topically administering to the subject a pharmaceutical composition comprising 0.01-5 wt % of detomidine.