US 12,239,626 B2
Method for treating infectious diseases with isothiocyanate functional compounds
Michael E. Silver, Lake City, MI (US)
Assigned to The William Yarbrough Foundation, Peoria, IL (US)
Filed by THE WILLIAM M YARBROUGH FOUNDATION, Peoria, IL (US)
Filed on Apr. 25, 2023, as Appl. No. 18/139,012.
Application 18/139,012 is a continuation of application No. 17/120,219, filed on Dec. 13, 2020, granted, now 11,633,375.
Application 17/120,219 is a continuation of application No. 16/453,972, filed on Jun. 26, 2019, granted, now 10,864,187, issued on Dec. 15, 2020.
Application 16/453,972 is a continuation of application No. 16/025,640, filed on Jul. 2, 2018, granted, now 10,335,387, issued on Jul. 2, 2019.
Application 16/025,640 is a continuation in part of application No. 15/838,444, filed on Dec. 12, 2017, granted, now 10,111,852, issued on Oct. 30, 2018.
Application 15/838,444 is a continuation of application No. 15/423,869, filed on Feb. 3, 2017, granted, now 9,839,621, issued on Dec. 12, 2017.
Application 15/423,869 is a continuation in part of application No. 14/867,626, filed on Sep. 28, 2015, granted, now 9,642,827, issued on May 9, 2017.
Application 14/867,626 is a continuation of application No. 14/867,585, filed on Sep. 28, 2015, granted, now 9,636,320, issued on May 2, 2017.
Application 14/867,585 is a continuation of application No. 14/519,510, filed on Oct. 21, 2014, granted, now 9,504,667, issued on Nov. 29, 2016.
Application 14/519,510 is a continuation of application No. 13/952,236, filed on Jul. 26, 2013, granted, now 8,865,772, issued on Oct. 21, 2014.
Claims priority of provisional application 61/676,093, filed on Jul. 26, 2012.
Prior Publication US 2023/0263763 A1, Aug. 24, 2023
Int. Cl. A61K 31/26 (2006.01); A61K 9/00 (2006.01); A61K 31/16 (2006.01); A61K 31/195 (2006.01); A61K 31/198 (2006.01)
CPC A61K 31/26 (2013.01) [A61K 9/0014 (2013.01); A61K 31/16 (2013.01); A61K 31/195 (2013.01); A61K 31/198 (2013.01)] 19 Claims
 
1. A method of treating an infectious disease comprising the step of:
administering a product that is a leave-on product or a leave-in product to a patient having an infectious disease wherein the product comprises an isothiocyanate functional surfactant and an additional surfactant, wherein the additional surfactant is chosen from the group consisting of a non-ionic surfactant, an anionic surfactant, a cationic surfactant, a zwitterionic surfactant, and combinations thereof; and
wherein the additional surfactant consists a non-ionic surfactant and the non-ionic surfactant is chosen from a group comprising alcohols, alkanolamides, amine oxides, esters, ethers, silicone copolyols, cetearyl alcohol, ceteareth-20, nonoxynol-9, C12-15 pareth-9, POE (4) lauryl ether, cocamide DEA, glycol distearate, glyceryl stearate, PEG-100 stearate, sorbitan stearate, PEG-8 laurate, polyglyceryl-10 trilaurate, lauryl glucoside, octylphenoxy-polyethoxyethanol, PEG-4 laurate, polyglyceryl diisostearate, polysorbate-60, PEG-200 isostearyl palmitate, sorbitan monooleate, polysorbate-80 and wherein the isothiocyanate functional surfactant is in a protonated form and wherein the protonated form of the isothiocyanate functional surfactant is represented by the following chemical structure:

OG Complex Work Unit Chemistry