	US 12,239,622 B2
	Compositions comprising amino acids for use in the prevention and treatment of liver diseases
Paolo Luca Maria Giorgetti, Milan (IT)
Assigned to PROFESSIONAL DIETETICS S.P.A., Milan (IT)
Appl. No. 17/255,887
Filed by Professional Dietetics International S.r.l., Milan (IT)
PCT Filed Apr. 2, 2019, PCT No. PCT/IB2019/052694 § 371(c)(1), (2) Date Dec. 23, 2020, PCT Pub. No. WO2020/003013, PCT Pub. Date Jan. 2, 2020.
Claims priority of application No. 102018000006725 (IT), filed on Jun. 27, 2018.
Prior Publication US 2021/0260011 A1, Aug. 26, 2021
Int. Cl. A61K 31/198 (2006.01); A61K 9/00 (2006.01); A61K 31/194 (2006.01); A61K 47/22 (2006.01); A61P 1/16 (2006.01)

CPC A61K 31/198 (2013.01) [A61K 9/0053 (2013.01); A61K 31/194 (2013.01); A61K 47/22 (2013.01); A61P 1/16 (2018.01)]

20 Claims

1. A method of treating liver cirrhosis, alcoholic liver disease (ALD) or non-alcoholic fatty liver disease (NAFLD), comprising administering to a subject in need thereof a therapeutic amount of a composition, wherein the composition comprises an active agent, said active agent containing the amino acids leucine, isoleucine, valine, threonine, lysine and the carboxylic acids citric acid, succinic acid, malic acid.