US 12,239,459 B2
Closed loop dialysis treatment using adaptive ultrafiltration rates
Louis LeeGrande Barrett, West Point, UT (US); Ken Chhi, Fremont, CA (US); David Yuds, Hudson, NH (US); Tom Merics, Antioch, CA (US); and Joan Dowd, Concord, CA (US)
Assigned to Fresenius Medical Care Holdings, Inc., Waltham, MA (US)
Filed by Fresenius Medical Care Holdings, Inc., Waltham, MA (US)
Filed on Nov. 30, 2020, as Appl. No. 17/107,892.
Application 17/107,892 is a continuation of application No. 15/927,769, filed on Mar. 21, 2018, granted, now 10,881,347.
Claims priority of provisional application 62/612,037, filed on Dec. 29, 2017.
Prior Publication US 2021/0077015 A1, Mar. 18, 2021
Int. Cl. A61B 5/00 (2006.01); A61B 5/0295 (2006.01); A61B 5/145 (2006.01); A61M 1/16 (2006.01); A61M 1/34 (2006.01)
CPC A61B 5/4836 (2013.01) [A61B 5/0295 (2013.01); A61B 5/14535 (2013.01); A61B 5/6866 (2013.01); A61M 1/1603 (2014.02); A61M 1/3403 (2014.02); A61B 5/14542 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method for performing closed-loop dialysis treatment, comprising:
determining, by a dialysis system, an initial ultrafiltration rate and setting an ultrafiltration pump to the determined initial ultrafiltration rate;
measuring, by the dialysis system, a total blood volume change based on the initial ultrafiltration rate;
determining, by the dialysis system, a benchmark blood volume threshold for the measured total blood volume change based on a target change in blood volume, a currently elapsed treatment time for the closed-loop dialysis treatment, a time duration associated with the closed-loop dialysis treatment, and a start time for the closed-loop dialysis treatment;
setting, by the dialysis system, the ultrafiltration pump to a new pump rate based on comparing the determined benchmark blood volume threshold with the measured total blood volume change; and
stopping, by the dialysis system, the closed-loop dialysis treatment based on the target change in blood volume.