US 12,239,443 B2
Application of electrochemical impedance spectroscopy in sensor systems, devices, and related methods
Ning Yang, Los Angeles, CA (US); Raghavendhar Gautham, Northridge, CA (US); Bradley C. Liang, Los Angeles, CA (US); and Rajiv Shah, Rancho Palos Verdes, CA (US)
Assigned to Medtronic MiniMed, Inc., Northridge, CA (US)
Filed by Medtronic MiniMed, Inc., Northridge, CA (US)
Filed on Jan. 10, 2022, as Appl. No. 17/571,723.
Application 17/571,723 is a continuation of application No. 16/185,700, filed on Nov. 9, 2018, granted, now 11,234,624.
Application 16/185,700 is a continuation of application No. 15/701,775, filed on Sep. 12, 2017, granted, now 10,172,544, issued on Jan. 8, 2019.
Application 15/701,775 is a continuation of application No. 15/446,886, filed on Mar. 1, 2017, granted, now 9,801,576, issued on Oct. 31, 2017.
Application 15/446,886 is a continuation of application No. 15/154,560, filed on May 13, 2016, granted, now 9,625,415, issued on Apr. 18, 2017.
Application 15/154,560 is a continuation of application No. 13/778,416, filed on Feb. 27, 2013, granted, now 9,357,958, issued on Jun. 7, 2016.
Claims priority of provisional application 61/755,811, filed on Jan. 23, 2013.
Claims priority of provisional application 61/754,485, filed on Jan. 18, 2013.
Claims priority of provisional application 61/754,483, filed on Jan. 18, 2013.
Claims priority of provisional application 61/754,475, filed on Jan. 18, 2013.
Claims priority of provisional application 61/754,479, filed on Jan. 18, 2013.
Claims priority of provisional application 61/657,517, filed on Jun. 8, 2012.
Prior Publication US 2022/0133179 A1, May 5, 2022
Int. Cl. A61B 5/1495 (2006.01); A61B 5/00 (2006.01); A61B 5/0537 (2021.01); A61B 5/0538 (2021.01); A61B 5/145 (2006.01); A61B 5/1459 (2006.01); A61B 5/1473 (2006.01); A61B 5/1486 (2006.01); A61M 5/142 (2006.01); A61M 5/158 (2006.01); A61M 5/172 (2006.01); G01N 27/02 (2006.01); G01N 27/416 (2006.01); G01N 33/49 (2006.01); G01N 33/66 (2006.01); G01N 33/96 (2006.01); G01R 35/00 (2006.01); G08B 21/18 (2006.01)
CPC A61B 5/1495 (2013.01) [A61B 5/0537 (2013.01); A61B 5/0538 (2013.01); A61B 5/14503 (2013.01); A61B 5/14532 (2013.01); A61B 5/1459 (2013.01); A61B 5/1473 (2013.01); A61B 5/14865 (2013.01); A61B 5/4839 (2013.01); A61B 5/6849 (2013.01); A61B 5/6852 (2013.01); A61B 5/6886 (2013.01); A61B 5/7203 (2013.01); A61B 5/7221 (2013.01); A61B 5/7225 (2013.01); A61B 5/7242 (2013.01); A61B 5/746 (2013.01); A61M 5/14276 (2013.01); A61M 5/1582 (2013.01); A61M 5/1723 (2013.01); G01N 27/026 (2013.01); G01N 27/028 (2013.01); G01N 27/416 (2013.01); G01N 27/4163 (2013.01); G01N 33/49 (2013.01); G01N 33/66 (2013.01); G01N 33/96 (2013.01); G01R 35/00 (2013.01); G01R 35/005 (2013.01); G08B 21/182 (2013.01); A61B 2562/0214 (2013.01); A61B 2562/04 (2013.01); A61M 5/14244 (2013.01); A61M 2005/1726 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method of calibration of a glucose sensor involving low start-up detection, the method comprising:
performing electrochemical impedance spectroscopy (EIS) procedures for a working electrode of the glucose sensor to obtain values of at least one impedance-based parameter for the working electrode;
performing a bound check for a Nyquist slope and a real impedance value at 1 kHz based on the at least one impedance-based parameter to calculate a reliability index;
performing a first calibration of the glucose sensor in a case where the reliability index is higher than a predetermined threshold; and
in a case where the reliability index is not higher than the predetermined threshold:
calculating a length of time for the Nyquist slope and the real impedance value at 1 kHz to be within a respective range;
performing the first calibration of the glucose sensor in a case where the length of time is shorter than a predetermined duration; and
performing a second calibration with an EIS-based calibration factor adjustment in a case where the length of time is not shorter than the predetermined duration.