	US 12,239,365 B2
	Electroporation for obesity or diabetes treatment
Christopher V. Desimone, Rochester, MN (US); Barham K. Abu Dayyeh, Rochester, MN (US); and Samuel J. Asirvatham, Rochester, MN (US)
Assigned to Mayo Foundation for Medical Education and Research, Rochester, MN (US)
Filed by Mayo Foundation for Medical Education and Research, Rochester, MN (US)
Filed on Nov. 17, 2021, as Appl. No. 17/529,037.
Application 17/529,037 is a continuation of application No. 15/766,604, granted, now 11,337,749, previously published as PCT/US2016/055966, filed on Oct. 7, 2016.
Claims priority of provisional application 62/238,191, filed on Oct. 7, 2015.
Prior Publication US 2022/0071700 A1, Mar. 10, 2022
Int. Cl. A61B 18/14 (2006.01); A61B 1/00 (2006.01); A61B 90/00 (2016.01); A61N 1/32 (2006.01); A61N 1/36 (2006.01); A61B 18/00 (2006.01); A61B 18/12 (2006.01); A61M 25/10 (2013.01)

CPC A61B 18/1492 (2013.01) [A61B 1/00082 (2013.01); A61B 1/00151 (2013.01); A61B 90/361 (2016.02); A61N 1/327 (2013.01); A61N 1/36007 (2013.01); A61B 2018/00065 (2013.01); A61B 2018/00083 (2013.01); A61B 2018/0016 (2013.01); A61B 2018/0022 (2013.01); A61B 2018/00238 (2013.01); A61B 2018/00261 (2013.01); A61B 2018/00285 (2013.01); A61B 2018/00494 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00613 (2013.01); A61B 2018/00839 (2013.01); A61B 2018/00982 (2013.01); A61B 2018/126 (2013.01); A61B 2018/1467 (2013.01); A61B 2018/1472 (2013.01); A61B 2090/3966 (2016.02); A61B 2218/002 (2013.01); A61M 2025/1004 (2013.01); A61M 25/1011 (2013.01); A61M 2025/1015 (2013.01); A61M 25/10181 (2013.11); A61M 2025/105 (2013.01); A61M 2025/1052 (2013.01); A61M 2025/1079 (2013.01)]

25 Claims

1. A method of treating diabetes in a patient, comprising:

advancing an electroporation device comprising one or more electrodes into a duodenum of the patient; and

delivering electroporation energy to mucosa of the duodenum using the one or more electrodes to treat diabetes, wherein the electroporation energy is delivered to crypts of the mucosa of the duodenum.