| CPC A61B 18/1477 (2013.01) [A61B 5/201 (2013.01); A61B 5/388 (2021.01); A61B 5/6852 (2013.01); A61B 17/2202 (2013.01); A61B 17/320068 (2013.01); A61B 18/06 (2013.01); A61B 18/1492 (2013.01); A61B 90/39 (2016.02); A61B 5/021 (2013.01); A61B 5/024 (2013.01); A61B 5/6848 (2013.01); A61B 2017/22014 (2013.01); A61B 2018/00214 (2013.01); A61B 2018/00404 (2013.01); A61B 2018/00434 (2013.01); A61B 2018/00511 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00666 (2013.01); A61B 2018/00738 (2013.01); A61B 2018/00779 (2013.01); A61B 2018/00791 (2013.01); A61B 2018/00827 (2013.01); A61B 2018/00839 (2013.01); A61B 2018/00875 (2013.01); A61B 2018/00892 (2013.01); A61B 2018/00898 (2013.01); A61B 2018/0212 (2013.01); A61B 18/0218 (2013.01); A61B 2018/046 (2013.01); A61B 2018/1425 (2013.01); A61B 2018/143 (2013.01); A61B 2018/1432 (2013.01); A61B 18/1815 (2013.01); A61B 2090/3966 (2016.02); A61M 2025/0087 (2013.01); A61N 7/022 (2013.01)] | 23 Claims |

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1. A method comprising:
advancing a distal portion of a catheter having at least three needle guide elements and at least three needles to a site within a human body;
advancing the at least three needle guide elements to expand outwardly against tissue within the human body, wherein the at least three needle guide elements are configured to maintain their position against the tissue;
advancing the at least three needles through the at least three needle guide elements into the tissue, wherein the at least three needle guide elements are configured to maintain their position against the tissue as the at least three needles are advanced into the tissue; and
ablating sympathetic nerve fibers while minimizing or eliminating pain to the patient.
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