US RE49,848 E1
System and methods for medicament infusion
Irio Giuseppe Calasso, Arth (CH); and Luca Calasso, Zurich (CH)
Assigned to Medirio S.A., Visp (CH)
Appl. No. 17/161,330
Filed by Medirio SA, Visp (CH)
PCT Filed Dec. 24, 2009, PCT No. PCT/CH2009/000411
§ 371(c)(1), (2), (4) Date May 24, 2012,
PCT Pub. No. WO2010/072010, PCT Pub. Date Jul. 1, 2010.
Application 17/161,330 is a reissue of application No. 13/139,843, filed on Dec. 24, 2009, granted, now 10,188,788, issued on Jan. 29, 2019.
Claims priority of application No. PCTCH2008000550 (WO), filed on Dec. 24, 2008.
Int. Cl. A61M 5/14 (2006.01); A61M 5/142 (2006.01); A61M 5/145 (2006.01); A61M 5/168 (2006.01); A61M 5/20 (2006.01); A61M 5/50 (2006.01)
CPC A61M 5/1413 (2013.01) [A61M 5/14 (2013.01); A61M 5/14244 (2013.01); A61M 5/14248 (2013.01); A61M 5/168 (2013.01); A61M 5/20 (2013.01); A61M 5/50 (2013.01); A61M 2005/14268 (2013.01); A61M 2005/2073 (2013.01); A61M 2205/8237 (2013.01); A61M 2205/8287 (2013.01)] 34 Claims
OG exemplary drawing
 
1. A [ drug delivery ] system for trans-dermal delivery of a dose of a medicament, comprising [ : ]
a delivery device [ ; ] and
a separate hand-held drive device, wherein
the delivery device is configured to be placed in dermal contact with a patient, the delivery device comprising [ comprises: ]
a reservoir for holding the [ a ] medicament to be delivered, [ and; ]
a trans-dermal injection element for delivering the dose of the medicament to the patient,
a control unit for controlling the transformation of external energy transferred from the hand-held drive device to the delivery device into a pumping force and for allowing a specific dose of the medicament to be pumped when the dose is requested, the control unit comprising [ : ]
one or more rotors and/or one or more [ a rotor or an ] axial pump elements for transforming rotational and/or axial force into the pumping force, [ element; ] and
at least one [ a ] safe-lock mechanism [ means ] for preventing mechanical action to cause rotation of the at least one or more rotors and/or [ rotor or ] movement of the one or more axial pump elements [ element, ] thereby preventing passage [ delivery ] of the medicament from the reservoir to the trans-dermal injection element unless a dose is requested; [ and ]
[ wherein ] the separate hand-held drive device being [ is ] configured to be placed temporarily in proximity to the delivery device when a dose of medicament is required, the hand-held [ separate ] drive device comprising [ : ]
an activation unit for activating the control unit of the delivery device, the activation unit comprising at least one unlocking element to [ configured to (i) ] provide energy to the control unit of the delivery device for unlocking the at least one safe-lock mechanism [ means ] and a drive unit to [ (ii) ] provide energy for any of the one or more rotors and/or one or more [ the rotor or the ] axial pump elements [ element ] of the control unit only when the separate hand-held drive device is in proximity to the delivery device , [ ; ] and wherein the hand-held drive device comprises a sensor capable of detecting the amount of energy being transferred and/or [ or ] transformed into pumping force.