	US 11,913,015 B2
	Embryonic cell cultures and methods of using the same
Chi-Hun Park, Laurel, MD (US); and Bhanu Prakash V. L. Telugu, Columbia, MD (US)
Assigned to UNIVERSITY OF MARYLAND, COLLEGE PARK, College Park, MD (US)
Appl. No. 16/606,199
Filed by UNIVERSITY OF MARYLAND, COLLEGE PARK, College Park, MD (US)
PCT Filed Apr. 17, 2018, PCT No. PCT/US2018/028041 § 371(c)(1), (2) Date Oct. 17, 2019, PCT Pub. No. WO2018/195129, PCT Pub. Date Oct. 25, 2018.
Claims priority of provisional application 62/486,325, filed on Apr. 17, 2017.
Prior Publication US 2021/0163992 A1, Jun. 3, 2021
Int. Cl. C12N 15/877 (2010.01); A01K 67/027 (2006.01); C12N 5/073 (2010.01)

CPC C12N 15/877 (2013.01) [A01K 67/027 (2013.01); C12N 5/0605 (2013.01); C12N 2510/00 (2013.01); C12N 2830/008 (2013.01)]

11 Claims

1. A composition comprising an isolated extraembryonic endodermal (XEN) cell;

wherein the isolated XEN cell is a porcine cell; and

wherein the isolated XEN cell comprises a phenotype of CDX2−, NANOG−, SOX2−, GATA4+, FOXA2+, GATA6+, SALL4+ and SOX17+.