US 11,912,994 B2
Methods for reactivating genes on the inactive X chromosome
Jeannie T. Lee, Boston, MA (US); Anand Minajigi, Boston, MA (US); and Lieselot Carrette, Beernem (BE)
Assigned to The General Hospital Corporation, Boston, MA (US)
Filed by The General Hospital Corporation, Boston, MA (US)
Filed on Mar. 26, 2021, as Appl. No. 17/214,320.
Application 17/214,320 is a division of application No. 15/565,060, granted, now 10,961,532, previously published as PCT/US2016/026218, filed on Apr. 6, 2016.
Claims priority of provisional application 62/181,083, filed on Jun. 17, 2015.
Claims priority of provisional application 62/168,528, filed on May 29, 2015.
Claims priority of provisional application 62/144,219, filed on Apr. 7, 2015.
Prior Publication US 2023/0020545 A1, Jan. 19, 2023
Int. Cl. C12N 15/113 (2010.01); C12N 9/10 (2006.01); C12Q 1/6883 (2018.01); C12N 9/90 (2006.01)
CPC C12N 15/113 (2013.01) [C12N 9/1007 (2013.01); C12N 9/90 (2013.01); C12Q 1/6883 (2013.01); C12Y 201/01037 (2013.01); C12Y 599/01002 (2013.01); C12N 2310/113 (2013.01); C12N 2310/14 (2013.01); C12N 2310/20 (2017.05); C12N 2310/3231 (2013.01); C12N 2310/531 (2013.01); C12N 2320/34 (2013.01); C12Q 2600/156 (2013.01)] 15 Claims
 
1. A composition comprising a DNMT Inhibitor and an inhibitory nucleic acid targeting XIST RNA.