US 11,912,968 B2
Microcavity dishes with sidewall including liquid medium delivery surface
Gregory Roger Martin, Acton, ME (US); and Allison Jean Tanner, Portsmouth, NH (US)
Assigned to CORNING INCORPORATED, Corning, NY (US)
Appl. No. 16/629,665
Filed by CORNING INCORPORATED, Corning, NY (US)
PCT Filed Jul. 13, 2018, PCT No. PCT/US2018/041985
§ 371(c)(1), (2) Date Jan. 9, 2020,
PCT Pub. No. WO2020/013847, PCT Pub. Date Jan. 16, 2020.
Prior Publication US 2021/0062126 A1, Mar. 4, 2021
Int. Cl. C12M 1/22 (2006.01); C12M 1/00 (2006.01); B29C 33/42 (2006.01)
CPC C12M 23/10 (2013.01) [C12M 29/00 (2013.01); B29C 33/42 (2013.01)] 12 Claims
OG exemplary drawing
 
8. A microcavity dish for cultivating cells, the microcavity dish comprising:
a dish body comprising a sidewall that encloses a cell culture chamber within the dish body, the dish body having a top and a bottom, wherein the bottom comprises a cell culturing substrate comprising an array of microcavities, wherein the sidewall extends from the bottom to the top of the dish body and wherein the cell culturing substrate is formed separately from the dish body and is connected thereto; and
a liquid delivery track that extends along the sidewall and at least partially along the cell culture chamber defining a liquid medium delivery surface, wherein the liquid delivery track has a first end nearer to the top than the bottom of the dish body and an opposite second end nearer to the bottom than the top of the dish body, and wherein the liquid delivery track extends at least partially along an interior surface of the sidewall and slopes along a length of the liquid delivery track downwardly from the first end to the second end and toward the bottom;
wherein the liquid medium delivery surface is on a portion of the sidewall above the array of microcavities.