US 11,912,788 B2
Probiotic molecules for reducing pathogen virulence
Monica Angela Cella, Stratford (CA); Sarah M. Curtis, Atikokan (CA); and Jonathon Patrick Roepke, Charlottetown (CA)
Assigned to MICROSINTESIS INC., Oakville (CA)
Appl. No. 16/494,429
Filed by MICROSINTESIS INC., Oakville (CA)
PCT Filed Mar. 16, 2018, PCT No. PCT/CA2018/050320
§ 371(c)(1), (2) Date Sep. 16, 2019,
PCT Pub. No. WO2018/165765, PCT Pub. Date Sep. 20, 2018.
Claims priority of provisional application 62/472,061, filed on Mar. 16, 2017.
Prior Publication US 2020/0017547 A1, Jan. 16, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 7/06 (2006.01); A23L 33/18 (2016.01); A23L 33/195 (2016.01); A61L 15/46 (2006.01); A61L 27/54 (2006.01); A61L 29/16 (2006.01); A61L 31/16 (2006.01); C07K 5/107 (2006.01); C07K 5/113 (2006.01); A61K 38/00 (2006.01)
CPC C07K 7/06 (2013.01) [A23L 33/18 (2016.08); A23L 33/195 (2016.08); A61L 15/46 (2013.01); A61L 27/54 (2013.01); A61L 29/16 (2013.01); A61L 31/16 (2013.01); C07K 5/1016 (2013.01); C07K 5/1021 (2013.01); A61K 38/00 (2013.01); A61L 2300/25 (2013.01); A61L 2300/404 (2013.01)] 7 Claims
 
1. An object for preventing and/or treating a non-enteric infection in a subject and/or reducing the virulence of a non-enteric infection in a subject, the object comprising a peptide produced by probiotic bacteria, the object being a stent, catheter, or wound dressing comprising the peptide, wherein the peptide is capable of preventing and/or treating the non-enteric infection in the subject and/or the peptide is capable of reducing the virulence of the non-enteric infection in the subject, and wherein the object is capable of releasing the peptide over a period of time.