CPC C07K 14/7051 (2013.01) [A61K 47/6851 (2017.08); C07K 14/465 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C12N 15/85 (2013.01); C07K 2319/00 (2013.01); C07K 2319/03 (2013.01); C07K 2319/20 (2013.01)] | 14 Claims |
1. An isolated biotin binding immune receptor (BBIR) comprising an extracellular binding domain, a transmembrane domain, a T cell receptor signaling domain, and an intracellular domain of a costimulatory molecule,
wherein the extracellular binding domain comprises avidin in monomeric or dimeric form,
wherein the BBIR comprises an amino acid sequence selected from the group consisting of SEQ ID NOs: 8-10.
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