US 11,912,683 B1
(6-methyl-4-substitutedphenyl-2-oxo/thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)(piperidin-1-yl)methanones as antitubercular agents
Katharigatta N. Venugopala, Al-Ahsa (SA); Keshab M. Bairagi, Maharashtra (IN); Pran Kishore Deb, Mesra (IN); Melendran Pillay, Durban (ZA); Mohamed A. Morsy, Al-Ahsa (SA); Susanta K. Nayak, Maharashtra (IN); Sandeep Chandrashekharappa, Raebareli (IN); and Osama I. Alwassil, Riyadh (SA)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Sep. 13, 2023, as Appl. No. 18/367,645.
Int. Cl. C07D 401/06 (2006.01); A61P 31/06 (2006.01); C07D 403/06 (2006.01)
CPC C07D 401/06 (2013.01) [A61P 31/06 (2018.01); C07D 403/06 (2013.01)] 3 Claims
 
1. A compound having the formula I:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt, ester, stereoisomer, or solvate thereof, wherein:
R1 is trifluoromethyl;
R2 is selected from the group consisting of piperidine and pyrrolidine;
X is S; and
n is 1 or 2.