US 11,911,498 B2
Low pH skin care composition and methods of using the same
Lu Zhang, Singapore (SG); Sudeep Chakravarty, Singapore (SG); and Joseph Michael Zukowski, Blue Ash, OH (US)
Assigned to The Procter & Gamble Company, Cincinnati, OH (US)
Filed by The Procter & Gamble Company, Cincinnati, OH (US)
Filed on Mar. 29, 2021, as Appl. No. 17/215,988.
Application 17/215,988 is a continuation of application No. 16/891,491, filed on Jun. 3, 2020, granted, now 10,959,933.
Claims priority of provisional application 63/032,992, filed on Jun. 1, 2020.
Prior Publication US 2021/0369587 A1, Dec. 2, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 8/67 (2006.01); A61K 8/06 (2006.01); A61K 8/365 (2006.01); A61K 8/81 (2006.01); A61K 8/891 (2006.01); A61Q 17/04 (2006.01); A61Q 19/00 (2006.01); A61Q 19/02 (2006.01); A61Q 19/08 (2006.01); A61Q 19/10 (2006.01)
CPC A61K 8/675 (2013.01) [A61K 8/06 (2013.01); A61K 8/365 (2013.01); A61K 8/8147 (2013.01); A61K 8/891 (2013.01); A61Q 17/04 (2013.01); A61Q 19/00 (2013.01); A61Q 19/005 (2013.01); A61Q 19/007 (2013.01); A61Q 19/02 (2013.01); A61K 2800/28 (2013.01); A61K 2800/48 (2013.01); A61Q 19/008 (2013.01); A61Q 19/08 (2013.01); A61Q 19/10 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A low pH skin care composition, comprising:
a) about 0.1% to 10% of niacinamide;
b) about 0.1% to 5% of a pH buffer comprising lactic acid and sodium lactate;
c) about 0.1% to 5% of a polymer thickener comprising polyacrylate crosspolymer-6; and
d) about 0.1% to 20% of a silicone fluid having a kinematic viscosity of 100 cSt or less at 25° C.,
e) wherein the composition has a pH of about 2.0 to about 5.0 and exhibits a TRPV1 activation of less than about 10% according to the TRPV1 assay.