US 11,911,364 B2
Positive allosteric modulators of GABAA receptor
Immanuel Lerner, Jerusalem (IL); and Amit Michaeli, Jerusalem (IL)
Assigned to PEPTICOM LTD., Jerusalum (IL)
Appl. No. 17/278,393
Filed by PEPTICOM LTD., Jerusalem (IL)
PCT Filed Sep. 18, 2019, PCT No. PCT/IL2019/051036
§ 371(c)(1), (2) Date Mar. 22, 2021,
PCT Pub. No. WO2020/065642, PCT Pub. Date Apr. 2, 2020.
Claims priority of provisional application 62/735,983, filed on Sep. 25, 2018.
Prior Publication US 2021/0353592 A1, Nov. 18, 2021
Int. Cl. A61K 31/381 (2006.01)
CPC A61K 31/381 (2013.01) 4 Claims
 
1. A method of treating depression, addiction or epilepsy, the method comprising administering to a subject in need thereof a GABAA receptor-binding compound of the following formula (Compound 1):

OG Complex Work Unit Chemistry